Chapter 1 Introduction1
1.1 Organic Compounds 1
1.2 Features of Organic Compounds2
1.3 The Covalent Bond2
1.4 Structural Representations of Organic Compounds5
1.5 Functional Groups and Classification of Organic Compounds7
1.6 Isomerism8
1.7 Significance of Studying Organic Chemistry for Medical Students9
Chapter 2 Saturated Hydrocarbons:Alkanes and Cycloalkanes11
2.1 Classification of Hydrocarbons11
2.2 Alkanes12
2.3 Cycloalkanes 21
Chapter 3 Unsaturated Hydrocarbons:Alkenes,Alkynes and Aromatics26
3.1 Alkenes26
3.2 Alkynes32
3.3 Aromatic Hydrocarbons34
Chapter 4 Alcohols,Phenols,and Ethers41
4.1 Alcohols41
4.2 Phenols45
4.3 Ethers46
4.4 Thioalcohols and Disulfides48
Chapter 5 Aldehydes and Ketones52
5.1 Structure of Aldehydes and Ketones52
5.2 Nomenclature of Aldehydes and Ketones 52
5.3 Physical Properties of Aldehydes and Ketones54
5.4 Preparation of Aldehydes and Ketones 54
5.5 Chemical Properties of Aldehydes and Ketones55
Chapter 6 Carboxylic Acids and Acid Derivatives65
6.1 Introduction to Acids and Acid Derivatives65
6.2 Structure and Physical Properties of Carboxylic Acids67
6.3 Naming the Carboxylic Acids69
6.4 Reactions of Carboxylic Acids70
6.5 Reactions which yield carboxylic acids74
6.6 Nomenclature of Acid Derivatives74
6.7 Physical Properties of Carboxylic Acid Derivatives77
6.8 Chemical Properties of Carboxylic Acid Derivatives78
Chapter 7 Amines87
7.1 Classification and Nomenclature of Amines87
7.2.Structure of Amines88
7.3 Physical Properties of Amines89
7.4 Chemical Properties of Amines89
7.5.Aromatic Diazonium Salts92
7.6.Alkaloids92
Chapter 8 Optical Isomerism95
8.1.Optical Activity95
8.2.Molecular Chirality97
8.3 Nomenclature of Chiral Carbon Atoms98
8.4.Fischer Projections100
8.5 Assigning R or S Configuration to Fischer Projections101
8.6 Compounds Have Two or More Chiral Centers102
8.7 Chirality in the Biological World103
Chapter 9 Carbohydrates108
9.1 Structure and Names of Monosaccharides108
9.2.Disaccharides117
9.3.Polysaccharides119
Chapter 10 Lipids123
10.1 Triacylglycerol—Fats and Oils123
10.2 Chemical properties of triacylglycerol124
10.3 Fatty Acids in Triacylglycerols124
10.4.Glycerophospholipids126
10.5.Steroids127
Chapter 11 Amino Acid and Proteins130
11.1.Amino Acids130
11.2.Structures of Polypeptides134
11.3.Structures of Proteins136
Chapter 12 Nucleic Acids142
12.1.Pentose142
12.2 Heterocyclic Nitrogenous Bases142
12.3.Nucleosides142
12.4.Nucleotides143
12.5 Primary Structures of Nucleic Acids143
12.6 Secondary Structure of DNA144
12.7 Higher orders of DNA Structures145
12.8 The Roles of DNA and RNA in Genetic Process145
References146