[正版新书]正版书籍 宫颈癌前病变病理诊断要点 张瑜主编科学出版社9787030717610

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本书系统介绍了宫颈癌前病变的相关概念、病理诊断依据、鉴别诊断、免疫组织化学标记的意义等，并详细说明了避免误诊及混淆的病理诊断要点。同时,对宫颈癌相关内容，如鳞状细胞癌、腺癌等也加以介绍，以期形成较为完整的知识体系。

本书语言通俗、可读性强,适合病理医师、病理技师、妇产科医师、妇女保健科医师及相关专业研究生、住院医师规范化培训生、进修生学习和参考。

第#一章　概述 ····················································································· 1

第#一节　宫颈癌的现状··································································· 1

第二节　宫颈癌的筛查与预防 ························································· 1

第三节　宫颈癌发病的相关因素 ······················································ 2

第二章　宫颈组织病理学 ······································································ 3

第#一节　宫颈解剖学与组织学 ························································· 3

一、宫颈解剖学 ····································································· 3

二、宫颈组织学 ····································································· 4

第二节　人乳头瘤病毒致病机制与宫颈癌疫苗现状 ······························ 7

一、人乳头瘤病毒致病机制 ······················································ 7

二、宫颈癌疫苗现状 ······························································· 9

第三节　宫颈储备细胞及其与宫颈癌发生的关系 ································11

一、宫颈储备细胞的概念 ························································11

二、宫颈储备细胞的起源 ························································12

三、宫颈储备细胞的增生与癌变 ···············································12

第四节　宫颈鳞状上皮癌前病变 ·····················································16

一、鳞状上皮非典型增生 ························································16

二、鳞状细胞原位癌 ······························································17

三、CIN 的分级诊断标准及鉴别诊断 ·········································19

四、点评 ·············································································26

第五节　宫颈上皮化生··································································26

一、化生的定义 ····································································26

二、鳞状上皮化生 ·································································26

三、移行上皮化生 ·································································29

宫颈癌前病变病理诊断要点 vi

四、子宫内膜样上皮化生 ························································29

五、输卵管上皮化生 ······························································29

第六节　宫颈鳞状上皮病变 ···························································29

一、宫颈湿疣 ·······································································29

二、乳头状未成熟性鳞化 ························································32

三、鳞状上皮乳头状瘤 ···························································34

第七节　宫颈鳞状细胞癌 ······························································34

一、病因学与流行病学 ···························································35

二、危险因素 ·······································································35

三、临床特点 ·······································································36

四、浅表浸润性鳞状细胞癌 ·····················································36

五、浸润性鳞状细胞癌 ···························································39

六、少见组织类型 ·································································44

七、点评 ·············································································48

第八节　宫颈腺上皮癌前病变与浸润性腺癌 ······································48

一、宫颈腺癌的病因 ······························································48

二、宫颈高#级别腺上皮内病变 ··················································49

三、原位腺癌 ·······································································52

四、早期浸润性腺癌 ······························································53

五、浸润性腺癌 ····································································55

六、点评 ·············································································64

第九节　其他宫颈恶性肿瘤 ···························································64

一、神经内分泌癌 ·································································64

二、胚胎性横纹肌肉瘤 ···························································66

三、ping滑肌肉瘤 ····································································66

四、髓系肉瘤 ·······································································67

五、恶性淋巴瘤 ····································································67

六、未分化癌 ·······································································67

 　目　　录 vii

第三章　宫颈癌前病变的细胞学诊断 ······················································69

第#一节　细胞学分类及液基细胞学 ··················································69

一、细胞学分类的研究进展 ·····················································69

二、液基细胞学检测 ······························································70

三、宫颈细胞学 TBS 的主要内容（2001 年） ·······························71

第二节　鳞状细胞异常··································································73

一、非典型鳞状细胞 ······························································73

二、鳞状上皮内病变 ······························································75

三、鳞状细胞癌 ····································································79

四、点评 ·············································································81

第三节　腺细胞异常·····································································81

一、非典型腺细胞 ·································································82

二、宫颈管原位腺癌 ······························································84

三、宫颈管腺癌 ····································································85

四、点评 ·············································································85

第四节　良性细胞改变··································································86

一、微生物感染 ····································································86

二、反应性细胞改变 ······························································87

三、表皮细胞萎缩（伴或不伴有炎症） ······································88

四、子宫切除术后腺上皮细胞状况 ············································88

五、正常细胞 ·······································································88

参考文献 ··························································································91

缩略语 ·····························································································95